The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

May. 20, 2008
Applicants:

Hiroshi Suzuki, Osaka, JP;

Tomohiro Yoshinari, Osaka, JP;

Inventors:

Hiroshi Suzuki, Osaka, JP;

Tomohiro Yoshinari, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 31/44 (2006.01); A61K 31/485 (2006.01); A61K 47/12 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2013 (2013.01); A61K 9/2077 (2013.01); A61K 31/485 (2013.01); A61K 47/12 (2013.01);
Abstract

A process for advantageously producing tablets having an improved release property and an excellent stability to change with time is provided. The process is for producing tablets containing a morphinan compound represented by the Formula (I) below or pharmaceutically acceptable acid addition salt thereof and an acidic substance such as fumaric acid, maleic acid or adipic acid, and characterized in that the morphinan compound or a pharmaceutically acceptable acid addition salt thereof is granulated by wet granulation together with (an) excipient(s) prior to adding the acidic substance thereto.


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