The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Dec. 21, 2010
Ping Tong, Libertyville, IL (US);
Deliang Zhou, Vernon Hills, IL (US);
Geoff G. Z. Zhang, Vernon Hills, IL (US);
Katherine R. Heemstra, Chicago, IL (US);
Cristina M. Fischer, Wadsworth, IL (US);
Nathaniel D. Catron, Vernon Hills, IL (US);
Eric A. Schmitt, Libertyville, IL (US);
Yeshwant D. Sanzgiri, Gurnee, IL (US);
Ping Tong, Libertyville, IL (US);
Deliang Zhou, Vernon Hills, IL (US);
Geoff G. Z. Zhang, Vernon Hills, IL (US);
Katherine R. Heemstra, Chicago, IL (US);
Cristina M. Fischer, Wadsworth, IL (US);
Nathaniel D. Catron, Vernon Hills, IL (US);
Eric A. Schmitt, Libertyville, IL (US);
Yeshwant D. Sanzgiri, Gurnee, IL (US);
AbbVie Inc., North Chicago, IL (US);
Abstract
A pharmaceutical capsule comprises a shell having encapsulated therewithin a liquid solution of ABT-263 or a pharmaceutically acceptable salt thereof in a substantially non-ethanolic carrier that comprises as pharmaceutically acceptable excipients (a) at least one phospholipid, (b) at least one solubilizing agent for the at least one phospholipid, selected from the group consisting of glycols, glycerides and mixtures thereof, (c) at least one non-phospholipid surfactant and (d) at least one sulfur-containing antioxidant. The capsule is useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.