The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

Dec. 07, 2012
Applicant:

The Methodist Hospital Research Institute, Houston, TX (US);

Inventors:

Rita Elena Serda, Pearland, TX (US);

Ismail Mustafa Meraz, Pearland, TX (US);

Jianhua Gu, Houston, TX (US);

Xiaojun Xia, Houston, TX (US);

Haifa Shen, Bellaire, TX (US);

Tong Sun, Houston, TX (US);

Mauro Ferrari, Houston, TX (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 47/48 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
A61K 9/143 (2013.01); A61K 2039/55572 (2013.01); A61K 47/48861 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55561 (2013.01); A61K 47/48876 (2013.01); A61K 39/0011 (2013.01);
Abstract

Disclosed are mesoporous silicon multi-stage vehicles that comprise liposomal-based second-stage particles, as well as pharmaceutical compositions and formulations including such vectors for use in a variety of diagnostic and therapeutic indications. In particular embodiments, MSV comprising ligand decorated second-stage particles are provided for therapeutic methods including, for example, treatment of mammalian cancers, including those of the human breast.


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