The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Mar. 18, 2010
Joe Zhou, Shanghai, CN;
Jianyang Zhao, Shanghai, CN;
Jiuru Sun, Box Hill North, AU;
Jun Wang, Shanghai, CN;
Shaoxiong Wang, Shanghai, CN;
Xinxing MA, Shanghai, CN;
Jun Lin, Shanghai, CN;
Joe Zhou, Shanghai, CN;
Jianyang Zhao, Shanghai, CN;
Jiuru Sun, Box Hill North, AU;
Jun Wang, Shanghai, CN;
Shaoxiong Wang, Shanghai, CN;
Xinxing Ma, Shanghai, CN;
Jun Lin, Shanghai, CN;
Genor Biopharma Co. Ltd, Shanghai, CN;
Abstract
The disclosure provides a novel anti-angiogenesis fusion protein. The present invention combines a chimeric vascular endothelial cell growth factor (VEGF) receptor or a fragment thereof with a multimerizing component, which have a superior binding capacity with human VEGF and placental growth factor (PIGF). The fusion protein has improved stability, prolonged half-life and the ability to form multivalent interactions with VEGF, and can be used for anti-angiogenesis, treating VEGF related diseases and inhibiting tumor growth.