The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Jun. 20, 2012
Gregory J. Larosa, Newton, MA (US);
Christopher Horvath, Taunton, MA (US);
Walter Newman, Boston, MA (US);
S. Tarran Jones, Radlett, GB;
Siobhan H. O'brien, Bishops Stortford, GB;
Theresa O'keefe, Waltham, MA (US);
Gregory J. LaRosa, Newton, MA (US);
Christopher Horvath, Taunton, MA (US);
Walter Newman, Boston, MA (US);
S. Tarran Jones, Radlett, GB;
Siobhan H. O'Brien, Bishops Stortford, GB;
Theresa O'Keefe, Waltham, MA (US);
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.