The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Jul. 18, 2008
Applicants:
James Dodge, Shrewsbury, MA (US);
Marco A. Passini, Shrewsbury, MA (US);
Lamya Shihabuddin, Brighton, MA (US);
Seng H. Cheng, Natick, MA (US);
Inventors:
James Dodge, Shrewsbury, MA (US);
Marco A. Passini, Shrewsbury, MA (US);
Lamya Shihabuddin, Brighton, MA (US);
Seng H. Cheng, Natick, MA (US);
Assignee:
Genzyme Corporation, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); C12Y 301/04012 (2013.01);
Abstract
Lysosomal storage diseases can be successfully treated using intraventricular delivery of the enzyme which is etiologically deficient in the disease. The administration can be performed slowly to achieve maximum effect. Surprisingly, effects are seen on both sides of the blood-brain barrier, making this an ideal delivery means for lysosomal storage diseases which affect both brain and visceral organs.