The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Dec. 22, 2009
Raffaella Bagnod, Turin, IT;
Luca Beccaria, Turin, IT;
Luisa Bertarione Rava Rossa, Turin, IT;
Domenico Criscuolo, Milan, IT;
Chiara Lorenzetto, Turin, IT;
Valentina Mainero, Turin, IT;
Alessandra Marconi, Reggio Emilia, IT;
Carlo Pincelli, Modena, IT;
Silvio Traversa, Turin, IT;
Raffaella Bagnod, Turin, IT;
Luca Beccaria, Turin, IT;
Luisa Bertarione Rava Rossa, Turin, IT;
Domenico Criscuolo, Milan, IT;
Chiara Lorenzetto, Turin, IT;
Valentina Mainero, Turin, IT;
Alessandra Marconi, Reggio Emilia, IT;
Carlo Pincelli, Modena, IT;
Silvio Traversa, Turin, IT;
Creabilis S.A., Luxembourg, LU;
Abstract
The present invention relates to a process for the preparation of polymer conjugates of indolocarbaxole compounds, in particular of polymer conjugates of K-252a and derivatives thereof, by a synthetic route which results in a highly pure product, with a high product yield. In a further aspect the present invention relates to novel polymer conjugates of K-252a and derivatives thereof, wherein the chemical group linking the polymer unity to the K-252a or to the K-252a derivative compound is characterized by a 5-member oxazolidindionic cyclic structure. These novel polymer conjugates are obtained through the novel synthetic route with high purity and high yields.