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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8926946 B1

PDFFull Text
Date of Patent:
Jan. 06, 2015

Filed:

Jun. 04, 2010

Peptides for transport of therapeutics and their carriers in mouse models and humans

Applicants:

Silvia Muro Galindo, Silver Spring, MD (US);

Ming Meng, Baoding, CN;

Carmen Garnacho Montero, Sevilla, ES;

Inventors:

Silvia Muro Galindo, Silver Spring, MD (US);

Ming Meng, Baoding, CN;

Carmen Garnacho Montero, Sevilla, ES;

Assignee:

University of Maryland, College Park, College Park, MD (US);

Attorneys:

Hultquist, PLLC

Mary B. Grant

Primary Examiner:

Karlheinz R Skowronek

Assistant Examiner:

Schuyler Milton

Int. Cl.
CPC ...
A61K 31/7088 (2006.01); A61K 49/00 (2006.01); C12N 5/071 (2010.01); C12Q 1/02 (2006.01); A61K 38/02 (2006.01); A61K 31/70 (2006.01); A61K 35/76 (2006.01); A61K 35/74 (2006.01); A61K 35/00 (2006.01); A61K 38/43 (2006.01); A61K 9/46 (2006.01); C07K 7/08 (2006.01); C07K 7/06 (2006.01); C12N 15/12 (2006.01); C12N 15/11 (2006.01); C12N 15/63 (2006.01); A61P 3/10 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); A61P 7/02 (2006.01); A61P 11/00 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61K 47/42 (2006.01); A61K 9/127 (2006.01); A61K 9/16 (2006.01); A61K 9/50 (2006.01); A61K 9/51 (2006.01); A61K 38/47 (2006.01); A61K 47/48 (2006.01); A61K 51/12 (2006.01); C07K 16/28 (2006.01); B82Y 5/00 (2011.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1273 (2013.01); A61K 9/1605 (2013.01); A61K 9/5094 (2013.01); A61K 9/5107 (2013.01); A61K 38/47 (2013.01); A61K 47/48176 (2013.01); A61K 47/482 (2013.01); A61K 47/48215 (2013.01); A61K 47/48246 (2013.01); A61K 47/48561 (2013.01); A61K 51/1203 (2013.01); C07K 16/2821 (2013.01); A61K 2039/505 (2013.01); C07K 2317/77 (2013.01); Y10S 977/773 (2013.01); Y10S 977/906 (2013.01);
Abstract

A system for targeted delivery of agents (e.g., molecular probes, diagnostic agents, therapeutic agents, imaging agents, research or analytical compounds, enzymes, peptides, proteins, lipids, lipoproteins, sugars, hormones, vitamins, nucleic acids, viruses, bacteria, and/or cells) including use of a composition containing the agent and a targeting moiety, specific for a determinant at the target location. An exemplary composition of the system includes a targeting moiety of one of peptides γ3, 2γ3, 3γ3, A1, B7, B8, B9, B1O, and D6, specific for targeting ICAM-I. The system enables effective, versatile, and safe targeting and transport of agents. The system is useful in research applications, as well as in the context of translational science and clinical interventions.

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