The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

Apr. 29, 2011
Applicants:

Jan Roger Karlson, Oslo, NO;

Peer Børretzen, Nærsnes, NO;

Inventors:

Jan Roger Karlson, Oslo, NO;

Peer Børretzen, Nærsnes, NO;

Assignee:

Algeta ASA, Oslo, NO;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61K 51/02 (2006.01); C01F 13/00 (2006.01); A61K 51/12 (2006.01); G21G 1/00 (2006.01);
U.S. Cl.
CPC ...
C01F 13/00 (2013.01); A61K 51/1282 (2013.01); G21G 1/0005 (2013.01); A61K 51/00 (2013.01); G21G 2001/0094 (2013.01);
Abstract

The present invention provides a method for the generation ofRa of pharmaceutically tolerable purity comprising i) preparing a generator mixture comprisingAc,Th andRa; ii) loading said generator mixture onto a strong base anion exchange resin; iii) eluting saidRa from said strong base anion exchange resin using a first mineral acid in an alcoholic aqueous solution to give a first elutedRa solution; iv) loading theRa of the first elutedRa solution onto a strong acid cation exchange resin; and v) eluting theRa from said strong acid cation exchange resin using a second mineral acid in aqueous solution to provide a second eluted solution. The invention additionally provides products of corresponding purity and/or products obtained or obtainable by such a method.


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