The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2014

Filed:

Oct. 25, 2011
Applicants:

Lanny S. Liebeskind, Atlanta, GA (US);

Wenting Wu, Decatur, GA (US);

Zhihui Zhang, Downers Grove, IL (US);

Hao LI, Decatur, GA (US);

Angus A. Lamar, Atlanta, GA (US);

Inventors:

Lanny S. Liebeskind, Atlanta, GA (US);

Wenting Wu, Decatur, GA (US);

Zhihui Zhang, Downers Grove, IL (US);

Hao Li, Decatur, GA (US);

Angus A. Lamar, Atlanta, GA (US);

Assignee:

Emory University, Atlanta, GA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 211/08 (2006.01); C07H 1/00 (2006.01); C07D 213/82 (2006.01); C07D 233/90 (2006.01); C07D 295/192 (2006.01); C07D 307/52 (2006.01); C07F 7/18 (2006.01); C07H 21/02 (2006.01); C07K 1/00 (2006.01); C07K 1/02 (2006.01); C07K 5/062 (2006.01); C07K 5/065 (2006.01); C07K 5/068 (2006.01); C07K 5/072 (2006.01); C07K 5/087 (2006.01);
U.S. Cl.
CPC ...
C07H 1/00 (2013.01); C07D 213/82 (2013.01); C07D 233/90 (2013.01); C07D 295/192 (2013.01); C07D 307/52 (2013.01); C07F 7/1852 (2013.01); C07F 7/1856 (2013.01); C07H 21/02 (2013.01); C07K 1/003 (2013.01); C07K 1/02 (2013.01); C07K 5/06026 (2013.01); C07K 5/06034 (2013.01); C07K 5/0606 (2013.01); C07K 5/06078 (2013.01); C07K 5/06086 (2013.01); C07K 5/06104 (2013.01); C07K 5/0812 (2013.01);
Abstract

The disclosure relates to methods for producing amide bonds and reagents related thereto. In some embodiments, the disclosure relates to methods of producing an amide comprising mixing an O-silylated thionoester and an amine under conditions such that an amide is formed. In another embodiment, the disclosure relates to mixing a thiolacid, a silylating agent, and an amine under conditions such that an amide is formed.


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