The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2014
Filed:
Feb. 01, 2013
Applicant:
Onyx Therapeutics, Inc., San Francisco, CA (US);
Inventors:
Pasit Phiasivongsa, Brentwood, CA (US);
Louis C. Sehl, Redwood City, CA (US);
William Dean Fuller, San Diego, CA (US);
Guy J. Laidig, Menlo Park, CA (US);
Assignee:
Onyx Therapeutics, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 303/00 (2006.01); C07D 301/03 (2006.01); C07K 1/107 (2006.01); C07K 1/30 (2006.01); C07C 51/41 (2006.01); C07K 5/107 (2006.01); C07K 5/103 (2006.01); C07D 303/36 (2006.01); C07C 53/18 (2006.01); C07D 301/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1016 (2013.01); C07D 301/03 (2013.01); C07K 1/1075 (2013.01); C07K 1/306 (2013.01); C07C 51/412 (2013.01); C07K 5/1008 (2013.01); C07D 303/36 (2013.01); C07C 53/18 (2013.01); A61K 38/00 (2013.01); C07D 301/00 (2013.01);
Abstract
The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones are stereoselectively converted to the desired keto epoxides.
Phiasivongsa, Pasit. (2014). Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides (U.S. Patent No. 8921583). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8921583
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile