The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2014
Filed:
Oct. 18, 2012
Kowa Company, Ltd., Aichi, JP;
Takahisa Ogamino, Tokyo, JP;
Yukiyoshi Yamazaki, Tokyo, JP;
Shin Tanikawa, Tokyo, JP;
Ayumu Okuda, Tokyo, JP;
Tomoaki Fukuda, Tokyo, JP;
Okihisa Tokuda, Tokyo, JP;
Yoshiharu Miyake, Tokyo, JP;
Shinsuke Itoh, Tokyo, JP;
Hiroyuki Ishiwata, Tokyo, JP;
Kowa Company, Ltd., Aichi, JP;
Abstract
The present invention provides a novel compound represented by a general formula (1) as shown below, which has a glucokinase-activating action in the liver and pancreatic β-cells and which is useful as an agent for preventing and/or treating diseases caused by hyperglycemia, such as diabetes. A spiroindoline compound represented by the general formula (1), or a salt thereof, or a solvate of the compound or the salt: [wherein ring A represents a nitrogen-containing 5-10 membered heteroaryl group;Rand R, which are the same or different, each represent a hydrogen atom, a halogen atom, a halo Calkyl group, a Caryl group, a cyano group, a Calkyl group optionally having a substituent, a Calkenyl group optionally having a substituent, etc.; Rrepresents a hydrogen atom, a Calkyl group optionally having a substituent, etc.; and Rrepresents a hydrogen atom, a halogen atom, a Calkyl group optionally having a substituent, etc.]