The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2014
Filed:
Jul. 19, 2013
Applicant:
Genzyme Corporation, Cambridge, MA (US);
Inventors:
Scott F. Sneddon, Salem, MA (US);
John L. Kane, Maynard, MA (US);
Bradford H. Hirth, Littleton, MA (US);
Frederic Vinick, Mechanicville, NY (US);
Shuang Qiao, San Diego, CA (US);
Sharon R. Nahill, Belmont, MA (US);
John M. Williams, Hopkinton, MA (US);
Hans-Peter Biemann, Cambridge, MA (US);
Assignee:
Genzyme Corporation, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/53 (2006.01); A61P 19/02 (2006.01); A61K 31/196 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); C07D 403/14 (2006.01); C07D 233/64 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 233/64 (2013.01);
Abstract
The present invention provides compounds which are modulators of TNF-α signaling and methods of use thereof for treating a patient having a TNF-α mediated condition. The compounds can be represented by the following structural formulas: