The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2014

Filed:

Apr. 06, 2011
Applicants:

Graham Cumming, Middlesbrough, GB;

Narendra Kumar B. Patel, Brampton, CA;

Bryan T. Forrest, Burlington, CA;

Yong Liu, Oakville, CA;

Sze-wan LI, Toronto, CA;

Peter Brent Sampson, Oakville, CA;

Louise G. Edwards, Mississauga, CA;

Heinz W. Pauls, Oakville, CA;

Inventors:

Graham Cumming, Middlesbrough, GB;

Narendra Kumar B. Patel, Brampton, CA;

Bryan T. Forrest, Burlington, CA;

Yong Liu, Oakville, CA;

Sze-Wan Li, Toronto, CA;

Peter Brent Sampson, Oakville, CA;

Louise G. Edwards, Mississauga, CA;

Heinz W. Pauls, Oakville, CA;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 403/10 (2006.01); C07D 413/14 (2006.01); C07D 403/14 (2006.01); C07D 231/56 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61K 31/5377 (2013.01); C07D 413/14 (2013.01); C07D 231/56 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention is directed to novel synthetic methods for preparing a spiro cyclopropyl indolinone compound represented by Structural Formula (A): (A) or its pharmaceutically acceptable salt thereof. Also included are synthetic intermediates described herein.


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