The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2014

Filed:

Oct. 20, 2011
Applicants:

David B Weiner, Merion, PA (US);

Krystle Lang, Philadelphia, PA (US);

Jian Yan, Havertown, PA (US);

Ruxandra Draghia-akli, Brussels, BE;

Amir S Khan, Narberth, PA (US);

Inventors:

David B Weiner, Merion, PA (US);

Krystle Lang, Philadelphia, PA (US);

Jian Yan, Havertown, PA (US);

Ruxandra Draghia-Akli, Brussels, BE;

Amir S Khan, Narberth, PA (US);

Assignees:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inovio Pharmaceuticals, Inc., Plymouth Meeting, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 48/00 (2006.01); A61K 31/711 (2006.01); A61K 39/29 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/711 (2013.01); A61K 39/29 (2013.01); A61K 38/00 (2013.01); C07K 2319/02 (2013.01); C12N 2770/24234 (2013.01); A61K 2039/53 (2013.01);
Abstract

Improved anti-HCV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus HCV genotype 1a, including for example, NS4B, NS5A and NS5B. Pharmaceutical composition, recombinant vaccines comprising and live attenuated vaccines are disclosed as well methods of inducing an immune response in an individual against HCV are disclosed.


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