The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2014

Filed:

Apr. 16, 2010
Applicants:

Gregory Paul Nitzel, Mattawan, MI (US);

Robert Gerard Ankenbauer, Portage, MI (US);

Jay Gregory Calvert, Otsego, MI (US);

Donna Steuerwald Dunyak, Richland, MI (US);

Jacqueline Gayle Marx, Portage, MI (US);

Nancee Lois Oien, Kalamazoo, MI (US);

Douglas Steven Pearce, Kalamazoo, MI (US);

Mira Ivanova Stoeva, Portage, MI (US);

James Richard Thompson, Portage, MI (US);

Inventors:

Gregory Paul Nitzel, Mattawan, MI (US);

Robert Gerard Ankenbauer, Portage, MI (US);

Jay Gregory Calvert, Otsego, MI (US);

Donna Steuerwald Dunyak, Richland, MI (US);

Jacqueline Gayle Marx, Portage, MI (US);

Nancee Lois Oien, Kalamazoo, MI (US);

Douglas Steven Pearce, Kalamazoo, MI (US);

Mira Ivanova Stoeva, Portage, MI (US);

James Richard Thompson, Portage, MI (US);

Assignee:

Zoetis LLC, Florham Park, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/00 (2006.01); C12N 1/00 (2006.01); C12N 7/00 (2006.01); C07K 14/005 (2006.01); C07K 16/08 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); C07K 14/005 (2013.01); C07K 16/081 (2013.01); A61K 39/00 (2013.01); A61K 2039/53 (2013.01); C12N 2750/10021 (2013.01); C12N 2750/10022 (2013.01);
Abstract

The present invention is directed to novel nucleotide and amino acid sequences of Torque teno virus ('TTV'), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine TTV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include vaccines that provide TTV ORF1 protein, or peptide fragments thereof, as antigen.


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