The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2014

Filed:

Apr. 22, 2010
Applicants:

Yukinori Take, Aichi, JP;

Shinichi Koizumi, Aichi, JP;

Takako Okumura, Aichi, JP;

Kazuhiko Nonomura, Aichi, JP;

Inventors:

Yukinori Take, Aichi, JP;

Shinichi Koizumi, Aichi, JP;

Takako Okumura, Aichi, JP;

Kazuhiko Nonomura, Aichi, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); A61K 31/44 (2006.01); A01N 43/40 (2006.01); A01N 37/12 (2006.01); A01N 37/44 (2006.01); A61K 31/195 (2006.01); A01N 47/28 (2006.01); A61K 31/17 (2006.01); C07D 513/02 (2006.01); C07D 515/02 (2006.01); C07D 211/72 (2006.01); C07D 211/84 (2006.01); C07D 213/56 (2006.01); C07C 273/00 (2006.01); C07C 275/00 (2006.01); C07C 239/00 (2006.01); A61K 31/192 (2006.01); A61K 31/437 (2006.01); A61K 31/4412 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 31/437 (2013.01); A61K 31/4412 (2013.01);
Abstract

This invention provides a medicament for the treatment of cancer, which cause a reduction of cancer. This invention relates to use of a compound which has inhibitory activities against prostaglandin E2 receptor (EP4 receptor) and is represented by the following general formula (I), (II), (III), or (IV), or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt for the manufacture of a medicament for the treatment of cancer. The invention relates to a method for treatment of cancer comprising administering the compound or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt to humans or animals. The compound or a pharmaceutically acceptable salt thereof, or the pharmaceutical composition may be used in combination with one or more second active agents.


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