The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2014
Filed:
Nov. 28, 2008
Applicants:
Nathanael Gray, Boston, MA (US);
Jianming Zhang, Cambridge, MA (US);
Barun Okram, San Diego, CA (US);
Xianming Deng, Jamaica Plain, MA (US);
Jae Won Chang, San Diego, CA (US);
Inventors:
Nathanael Gray, Boston, MA (US);
Jianming Zhang, Cambridge, MA (US);
Barun Okram, San Diego, CA (US);
Xianming Deng, Jamaica Plain, MA (US);
Jae Won Chang, San Diego, CA (US);
Assignees:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
The Scripps Research Institute, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 495/04 (2006.01); C07D 239/42 (2006.01); C07D 239/94 (2006.01); A61K 31/519 (2006.01); A61K 31/517 (2006.01); A61K 31/5377 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 417/04 (2006.01); C07D 473/34 (2006.01); C07D 403/12 (2006.01); A61P 35/00 (2006.01); A61K 31/506 (2006.01); A61K 31/7076 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 239/94 (2013.01); C07D 495/04 (2013.01); C07D 403/04 (2013.01); C07D 239/42 (2013.01); C07D 473/34 (2013.01); C07D 417/04 (2013.01);
Abstract
The present invention provides novel heteroaryl compounds of formula (I) having a pyrimidine-containing core that is linked to a 4-trifluoromethoxyphenyl group via an amine linker. Such compounds are useful for the treatment of cancers.