The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2014

Filed:

Oct. 15, 2009
Applicants:

Jean-paul Castaigne, Mont-Royal, CA;

Michel Demeule, Beaconsfield, CA;

Catherine Gagnon, Montréal-Nord, CA;

Betty Lawrence, Bolton, CA;

Inventors:

Jean-Paul Castaigne, Mont-Royal, CA;

Michel Demeule, Beaconsfield, CA;

Catherine Gagnon, Montréal-Nord, CA;

Betty Lawrence, Bolton, CA;

Assignee:

Angiochem, Inc., Montreal, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 3/10 (2006.01); A61P 3/04 (2006.01); C07K 14/605 (2006.01); C07K 14/575 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07K 14/57563 (2013.01); C07K 2319/01 (2013.01); A61K 47/48338 (2013.01); A61K 47/48246 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a GLP-1 agonist (e.g., exendin-4 or an exendin-4 analog). The compounds of the invention can be used to treat any disease where increased GLP-1 activity is desired, for example, metabolic diseases, such as obesity and diabetes.


Find Patent Forward Citations

Loading…