The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2014
Filed:
Feb. 11, 2009
Applicant:
Daniel Irimia, Charlestown, MA (US);
Inventor:
Daniel Irimia, Charlestown, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/558 (2006.01); G01N 33/50 (2006.01); B01L 3/00 (2006.01); G01N 33/543 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
G01N 33/491 (2013.01); G01N 33/5029 (2013.01); B01L 2200/10 (2013.01); B01L 2400/0421 (2013.01); B01L 3/502776 (2013.01); G01N 33/54366 (2013.01); B01L 2400/0442 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/0816 (2013.01); B01L 2400/043 (2013.01); B01L 2300/0636 (2013.01); Y10S 436/805 (2013.01); Y10S 436/807 (2013.01);
Abstract
The present invention provides systems and methods for assessing migration behavior of biological particles, such as neutrophils, under the effect of a gradient. The systems can include one or more migration chambers, one or more gradient sources configured to generate particular gradients, e.g., of chemokines or the like across the width of the migration chamber, and a detection arrangement that is configured to determine spatial profiles across the migration chamber that indicate the extent of migration.