The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2014
Filed:
Apr. 26, 2010
Martin Kietzmann, Graz, AT;
Harald Pichler, Deutschlandsberg, AT;
Helmut Schwab, Graz, AT;
Amin El-heliebi, Graz, AT;
Christine Winkler, Graz, AT;
Andreas Braun, Graz, AT;
Martin Kietzmann, Graz, AT;
Harald Pichler, Deutschlandsberg, AT;
Helmut Schwab, Graz, AT;
Amin El-Heliebi, Graz, AT;
Christine Winkler, Graz, AT;
Andreas Braun, Graz, AT;
DSM IP Assets B.V., Heerlen, NL;
Abstract
The invention relates to an isolated polypeptide having esterase activity comprising an amino acid sequence shown in any one of SEQ ID NO's 2, 4, 6, 8, 10, 12 or 14 or a homologue thereof, comprising an amino acid substitution or deletion of one or more amino acids as shown in said SEQ ID NO's and resulting in a mutant polypeptide having an increased concentration of the fraction of the mutant polypeptide being present as an active and soluble protein in cleared lysate of the mutant polypeptide expressed inrelative to the concentration of the fraction of the polypeptide without the mutation being present as an active and soluble protein in cleared lysate of the polypeptide without the one or more deletion or substitution expressed inunder the same conditions. The invention also relates to nucleic acid encoding the polypeptides according to the invention, and the use of the polypeptides.