The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2014
Filed:
Oct. 06, 2004
David Morritz DE Kretser, Surrey Hills, AU;
David James Phillips, Hughesdale, AU;
Kristian Lee Jones, Hawthorn East, AU;
Robyn O'hehir, Melbourne, AU;
Shane Patella, Oakleigh, AU;
David Morritz De Kretser, Surrey Hills, AU;
David James Phillips, Hughesdale, AU;
Kristian Lee Jones, Hawthorn East, AU;
Robyn O'Hehir, Melbourne, AU;
Shane Patella, Oakleigh, AU;
Paranta Biosciences Limited, Richmond, Victoria, AU;
Abstract
The present invention relates generally to a method of modulating an inflammatory response in a mammal and to agents useful for same. More particularly, the present invention relates to a method of modulating an inflammatory response in a mammal by modulating the functional activity of activin and thereby modulating the pro-inflammatory mediator cascade. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterized by an aberrant, unwanted or otherwise inappropriate inflammatory response including, inter alia, sepsis and inflammation of the airway. The present invention is further directed to methods for identifying and/or designing agents capable of modulating activin mediated regulation of the inflammatory response.