The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2014
Filed:
Aug. 26, 2011
Applicant:
Masato Komiyama, Tokyo, JP;
Inventor:
Masato Komiyama, Tokyo, JP;
Assignee:
Teijin Pharma Limited, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/20 (2006.01); C07D 417/04 (2006.01); C07D 277/56 (2006.01); B01J 31/26 (2006.01);
U.S. Cl.
CPC ...
C07D 417/04 (2013.01); C07D 277/20 (2013.01); C07D 277/56 (2013.01); B01J 31/26 (2013.01);
Abstract
The present invention provides a method for producing a xanthine oxidase inhibitor, which is a therapeutic agent for hyperuricemia, or intermediates of the same, said method being efficient and using a short process. The present invention is a novel coupling method for obtaining a compound represented by formula (3) by bringing about a coupling reaction between a compound represented by formula (1) and a compound represented by formula (2), in the presence of a palladium compound, a ligand capable of coordinating to the palladium compound, a base, a C-Ccarboxylic acid, and at least one kind of additive.