The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2014

Filed:

Aug. 02, 2013
Applicant:

Johnson Matthey Public Limited Company, London, GB;

Inventors:

Nicolas Archer, Edinburgh, GB;

Maureen Young, Edinburgh, GB;

Timothy Davies, Edinburgh, GB;

Amy Price, Edinburgh, GB;

Michael Bease, Edinburgh, GB;

Barbara Jamieson, Edinburgh, GB;

Ewart Grant, Devens, MA (US);

Brian Heinrich, Devens, MA (US);

Saroop Matharu, Devens, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 489/08 (2006.01); C07D 489/02 (2006.01);
U.S. Cl.
CPC ...
C07D 489/08 (2013.01);
Abstract

The present invention provides a process for preparing an oxycodone acid adduct, said process comprising hydrogenating an aqueous solution of 14-hydroxycodeinone and an acid to form a solution of the oxycodone acid adduct, wherein the hydrogenation is carried out at one or more temperatures greater than ambient temperature in the presence of a hydrogenation catalyst and hydrogen gas, wherein the solution of oxycodone acid adduct comprises 6α-oxycodol in an amount ≦about 0.800 area % as determined by HPLC.


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