The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2014
Filed:
Dec. 15, 2011
Daniel Robert Fandrick, Danbury, CT (US);
Zhi-hui LU, Newtown, CT (US);
Diana Reeves, New Milford, CT (US);
Jonathan Reeves, New Milford, CT (US);
Chris Hugh Senanayake, Brookfield, CT (US);
Jinhua Jeff Song, Hopewell Junction, NY (US);
Yongda Zhang, Sandy Hook, CT (US);
Daniel Robert Fandrick, Danbury, CT (US);
Zhi-Hui Lu, Newtown, CT (US);
Diana Reeves, New Milford, CT (US);
Jonathan Reeves, New Milford, CT (US);
Chris Hugh Senanayake, Brookfield, CT (US);
Jinhua Jeff Song, Hopewell Junction, NY (US);
Yongda Zhang, Sandy Hook, CT (US);
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Abstract
Disclosed is a process for making diastereomeric compound of the formula (I): wherein m, n and Rto Rare as defined herein. The process of the invention provides the compound of formula (I) in high yield and substantially free of the corresponding diastereomers. The compounds of formula (I) prepared by the process of the invention are useful for making pharmaceutically active compounds such as 11-β-hydroxysteroid hydrogenase type 1 (11-β-HSD1) inhibitors.