The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2014

Filed:

Oct. 05, 2011
Applicants:

Bradley D. Olsen, Arlington, MA (US);

Matthew J. Glassman, Cambridge, MA (US);

Jacqueline Chan, Arcadia, CA (US);

Inventors:

Bradley D. Olsen, Arlington, MA (US);

Matthew J. Glassman, Cambridge, MA (US);

Jacqueline Chan, Arcadia, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2006.01); C07K 2/00 (2006.01); C07K 14/00 (2006.01); A61L 27/22 (2006.01); A61L 27/52 (2006.01);
U.S. Cl.
CPC ...
A61K 47/42 (2013.01); A61L 27/227 (2013.01); A61L 27/52 (2013.01);
Abstract

Described herein are block copolymer conjugates that form double-network hydrogels under appropriate conditions. The conjugates comprise a block of polymer end-group, a block of self-associating peptide or protein, and flexible linkers between the two. Hydrogels comprising the conjugates have the mechanical properties, including elastic modulus and fracture toughness, required for load-bearing applications, while maintaining desirable shear-thinning properties, for example, for injectability.


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