The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2014

Filed:

Feb. 07, 2013
Applicant:

Research & Business Foundation Sungkyunkwan University, Suwon-si, KR;

Inventors:

Doo Sung Lee, Gwacheon-si, KR;

Bong Sup Kim, Suwon-si, KR;

Cong Truc Huynh, Suwon-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G 71/04 (2006.01); C08G 18/38 (2006.01); C08G 18/42 (2006.01); C08G 18/73 (2006.01);
U.S. Cl.
CPC ...
C08G 71/04 (2013.01); C08G 18/3831 (2013.01); C08G 18/4269 (2013.01); C08G 18/73 (2013.01); C08G 2130/00 (2013.01);
Abstract

Disclosed is a dual-transition polymeric hydrogel. Also, provided is the use of the dual-transition polymeric hydrogel as a carrier for drug delivery and disease diagnosis, or in the preparation of a polymeric hydrogel-type pharmaceutical composition comprising the physiologically active agent loadable into the block copolymer. Being sensitive to pH as well as temperature, the block copolymer can form a more stable hydrogel at suitable temperatures and pH values. In addition, the block copolymer exhibits a dual transition behavior with pH values so that it can carry ionic drugs, proteins, DNA, and markers, whether positively or negatively charged, simultaneously. Therefore, it can be applied to a sustained drug delivery system for sparingly soluble, hydrophobic drugs, and hydrophilic drugs. Further, it is safe to and stable within the body, and is expected to find various applications in the medical field.


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