The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2014

Filed:

Dec. 01, 2011
Applicants:

Stephen B. Liggett, Clarksville, MD (US);

Michael Bristow, Englewood, CO (US);

Inventors:

Stephen B. Liggett, Clarksville, MD (US);

Michael Bristow, Englewood, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/405 (2006.01); A61K 47/00 (2006.01); A61P 43/00 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/172 (2013.01); C12Q 2600/156 (2013.01);
Abstract

The present invention concerns the use of methods for evaluating bucindolol treatment for a patient, particularly one with heart failure. It concerns methods for determining whether to administer or prescribe bucindolol to a patient based on whether the patient is homozygous for the Arg 389 polymorphism in the β1-adrenergic receptor (AR).


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