The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2014

Filed:

Jul. 22, 2013
Applicant:

Janssen Pharmaceutica N.v., Beerse, BE;

Inventors:

Patrick René´ Angibaud, Fontaine-Bellinger, FR;

Kristof Van Emelen, Sint-Niklaas, BE;

Virginie Sophie Poncelet, Le Manoir sur Seine, FR;

Bruno Roux, Saint Leger du Bourg-Denis, FR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); A61K 31/454 (2006.01); A61K 31/55 (2006.01); C12Q 1/48 (2006.01); C07D 217/16 (2006.01); C07D 307/68 (2006.01); C07D 239/42 (2006.01); A61K 45/06 (2006.01); C07D 295/26 (2006.01); A61K 31/495 (2006.01); C07D 471/04 (2006.01); C07D 401/04 (2006.01); A61K 31/472 (2006.01); C07D 295/155 (2006.01); A61K 31/496 (2006.01); C07D 409/12 (2006.01); C07D 207/09 (2006.01); C07D 513/04 (2006.01); A61K 31/5377 (2006.01); C07D 403/04 (2006.01); C07D 211/58 (2006.01); C07D 405/06 (2006.01); C07D 207/14 (2006.01); C07D 213/78 (2006.01); A61K 31/435 (2006.01); A61K 31/40 (2006.01); C07D 217/02 (2006.01); C07D 413/04 (2006.01); C07D 471/10 (2006.01); A61K 31/4427 (2006.01);
U.S. Cl.
CPC ...
A61K 31/40 (2013.01); A61K 31/454 (2013.01); A61K 31/55 (2013.01); C12Q 1/48 (2013.01); C07D 217/16 (2013.01); C07D 307/68 (2013.01); C07D 239/42 (2013.01); A61K 45/06 (2013.01); C07D 295/26 (2013.01); A61K 31/495 (2013.01); A61K 31/506 (2013.01); C07D 471/04 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); A61K 31/472 (2013.01); C07D 295/155 (2013.01); A61K 31/496 (2013.01); C07D 409/12 (2013.01); C07D 207/09 (2013.01); C07D 513/04 (2013.01); A61K 31/5377 (2013.01); C07D 403/04 (2013.01); C07D 211/58 (2013.01); C07D 405/06 (2013.01); C07D 207/14 (2013.01); C07D 213/78 (2013.01); A61K 31/435 (2013.01); C07D 217/02 (2013.01); C07D 413/04 (2013.01); C07D 471/10 (2013.01); A61K 31/4427 (2013.01);
Abstract

This invention comprises the novel compounds of formula (I) wherein n, m, t, R, R, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.


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