The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2014
Filed:
Feb. 23, 2010
Applicants:
Paulina Chorobik, Wieliczka, PL;
Joanna Bereta, Kraków, PL;
Inventors:
Michal Bereta, Kraków, PL;
Paulina Chorobik, Wieliczka, PL;
Assignee:
Jagiellonian University, Crakow, PL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C12N 1/20 (2006.01); A61K 39/112 (2006.01); A61K 39/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0275 (2013.01); A61K 2039/523 (2013.01); A61K 2039/522 (2013.01); A61K 39/0011 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to a new bacterial strain ofenterica serovarVNP20009 deposited in the Polish Collection of Microorganisms under access no. B/00024 and its us in the production of a vaccine, especially an anti-cancer vaccine. The present invention also relates to a method of obtaining a therapeutic vaccine vector, characterized in that a genetic modification is introduced into the vector strain specific to cancer cells, resulting in the delayed over expression of a gene encoding a protein responsible for the invasive ability of this strain.