The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2014
Filed:
Aug. 07, 2012
Yama A. Abassi, San Diego, CA (US);
Naichen Yu, San Diego, CA (US);
Josephine Atienza, San Diego, CA (US);
Xiao Xu, San Diego, CA (US);
Xiaobo Wang, San Diego, CA (US);
Yama A. Abassi, San Diego, CA (US);
Naichen Yu, San Diego, CA (US);
Josephine Atienza, San Diego, CA (US);
Xiao Xu, San Diego, CA (US);
Xiaobo Wang, San Diego, CA (US);
ACEA Biosciences, Inc., San Diego, CA (US);
Abstract
Methods for identifying a compound capable of interacting with a Receptor Tyrosine Kinase (RTK) including providing a device capable of measuring cell-substrate impedance, adding test cells expressing a RTK to the device, measuring first impedances, adding a compound to at least one compound well and adding a vehicle control to at least one control well, measuring second impedances of the compound well and the control well, determining the change in the impedance for the compound well and the one control well, comparing the change in impedance between the compound well and the control well, and identifying the compound interacts with the RTK if the comparison demonstrates a significant difference between the change in impedance.