The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2014

Filed:

Nov. 04, 2013
Applicant:

Allied Innovative Systems, Llc, Budd Lake, NJ (US);

Inventors:

Simon Bystryak, Budd Lake, NJ (US);

Rasa Santockyte, Princeton, NJ (US);

Assignee:

Allied Innovative Systems, LLC, Budd Lake, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/00 (2006.01); C12Q 1/00 (2006.01); G01N 33/542 (2006.01); C12Q 1/28 (2006.01); C12Q 1/68 (2006.01); C12Q 1/70 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/542 (2013.01); C12Q 1/28 (2013.01); C12Q 1/682 (2013.01); C12Q 1/703 (2013.01); G01N 33/56911 (2013.01); G01N 33/56988 (2013.01); Y10S 436/905 (2013.01);
Abstract

An improved assay for detecting an analyte in a fluid sample includes a step of conducting a photochemical reaction, in which a substrate conversion catalyzed by a photosensitizer into a product of the photochemical reaction is temporary inhibited when the reaction mixture is irradiated with a light at a wavelength within a light absorption spectrum of the photosensitizer. The photosensitizer (or an enzyme to catalyze producing thereof) is attached to an entity having an affinity to the analyte, such entity is bound to the analyte prior to irradiation. The assay may increase the sensitivity of ELISA 20- to 100-fold.


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