The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2014
Filed:
Mar. 17, 2011
Peter D. Walzer, Loveland, OH (US);
Melanie T. Cushion, Miami Township, OH (US);
Annie Mayence, Mons, BE;
Tien Liang Huang, Metairie, LA (US);
Jean Jacques Vanden Eynde, Mons, BE;
Peter D. Walzer, Loveland, OH (US);
Melanie T. Cushion, Miami Township, OH (US);
Annie Mayence, Mons, BE;
Tien Liang Huang, Metairie, LA (US);
Jean Jacques Vanden Eynde, Mons, BE;
University of Cincinnati, Cincinnati, OH (US);
Xavier University, New Orleans, LA (US);
Abstract
A method of combating infectious agents, such aspneumonia, and a method of treating a subject in need of such treatment is disclosed. The method comprises administering to the subject a bis-benzamidoxime of formula I wherein the linker is a di-substituted cyclic moiety of any ring size and may contain at least one heteroatom; the aromatic group is 1,2-; 1,3-; or 1,4-disubstituted; R is selected from the group consisting of a hydrogen, a linear or branched alkyl group, containing from 1 to 20 carbon atoms; R' is selected from the group consisting of a hydrogen, a linear or branched alkyl group containing from one to twenty carbon atoms, an aromatic ring, a cycloalkyl group containing three to eight carbon atoms, or a hydroxyl group; alternatively, R and R′ may form a cyclic structure that can be fused to another cyclic system; or a pharmaceutically acceptable salt thereof. Pharmaceutical formulations and active compounds useful in the practice of the present invention are also disclosed.