The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2014
Filed:
May. 04, 2012
Applicants:
Marcello Rasparini, Cura Carpignano, IT;
Roberto Rocco Tufaro, Sozzago, IT;
Cosima Minelli, Somma Lombardo, IT;
Inventors:
Marcello Rasparini, Cura Carpignano, IT;
Roberto Rocco Tufaro, Sozzago, IT;
Cosima Minelli, Somma Lombardo, IT;
Assignee:
Chemo Iberica, S.A., Barcelona, ES;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 263/26 (2006.01); C07C 67/30 (2006.01); C07C 263/12 (2006.01); C07C 269/02 (2006.01); C07C 269/06 (2006.01); C07C 69/65 (2006.01); C07C 69/612 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 263/26 (2013.01); C07C 67/30 (2013.01); C07C 263/12 (2013.01); C07C 269/02 (2013.01); C07C 269/06 (2013.01); C07C 69/65 (2013.01); C07C 69/612 (2013.01);
Abstract
A novel process is described for the synthesis of Sitagliptin, IUPAC name 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1 2,4-triazolo[4,3-a]pyrazine, of formula (I).