The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2014

Filed:

Nov. 10, 2011
Applicants:

Bingming He, Shanghai, CN;

Ming LI, Shanghai, CN;

Zhijun Tang, Shanghai, CN;

Xiaoming Ji, Shanghai, CN;

Inventors:

Bingming He, Shanghai, CN;

Ming Li, Shanghai, CN;

Zhijun Tang, Shanghai, CN;

Xiaoming Ji, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/113 (2006.01); C07K 7/56 (2006.01); C07K 7/64 (2006.01);
U.S. Cl.
CPC ...
C07K 7/64 (2013.01); C07K 7/56 (2013.01);
Abstract

Disclosed is a preparation method for caspofungin, comprising the steps: (a) a compound as represented in Formula 2 and a strong leaving group 5 are mixed to obtain a compound as represented in Formula 3; (b) the compound as represented in Formula 3 and ethylenediamine are mixed to obtain a compound as represented in Formula 4; and, (c) the compound as represented in Formula 4 is mixed with a hydroxyl protection agent, and then a borane complex is mixed in to obtain a compound as represented in Formula 1.


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