The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2014

Filed:

Jul. 18, 2012
Applicants:

Maria Gabriella Brasca, Nerviano, IT;

Jay Aaron Bertrand, Didcot, GB;

Paola Gnocchi, Stresa, IT;

Ilaria Motto, Nerviano, IT;

Marcella Nesi, Saronno, IT;

Achille Panzeri, Merate, IT;

Paola Vianello, Milan, IT;

Inventors:

Maria Gabriella Brasca, Nerviano, IT;

Jay Aaron Bertrand, Didcot, GB;

Paola Gnocchi, Stresa, IT;

Ilaria Motto, Nerviano, IT;

Marcella Nesi, Saronno, IT;

Achille Panzeri, Merate, IT;

Paola Vianello, Milan, IT;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); A61K 45/06 (2006.01); A61K 31/506 (2006.01); C07D 417/14 (2006.01); C07D 403/04 (2006.01); C07D 405/14 (2006.01); A61K 31/541 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/541 (2013.01); A61K 45/06 (2013.01); A61K 31/506 (2013.01); C07D 417/14 (2013.01); C07D 403/04 (2013.01); C07D 405/14 (2013.01); C07D 403/14 (2013.01);
Abstract

The present invention relates to alkynyl substituted pyrimidinyl-pyrrole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular Jak and/or Src family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.


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