The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2014

Filed:

Oct. 16, 2009
Applicants:

Matthias Engel, Zweibrücken, DE;

Wolfgang Fröhner, Saarbrücken, DE;

Adriane Stroba, Nohfelden, DE;

Ricardo M. Biondi, Frankfurt, DE;

Inventors:

Matthias Engel, Zweibrücken, DE;

Wolfgang Fröhner, Saarbrücken, DE;

Adriane Stroba, Nohfelden, DE;

Ricardo M. Biondi, Frankfurt, DE;

Assignee:

Universitaet des Saarlandes, Saarbruecken, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/58 (2006.01); A61K 31/50 (2006.01); C07C 59/88 (2006.01); C07C 59/90 (2006.01); C07D 213/55 (2006.01); C07D 307/80 (2006.01); C07D 333/56 (2006.01); C07D 209/18 (2006.01);
U.S. Cl.
CPC ...
C07D 209/18 (2013.01); C07C 59/88 (2013.01); C07C 59/90 (2013.01); C07D 213/55 (2013.01); C07D 307/80 (2013.01); C07D 333/56 (2013.01);
Abstract

The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.


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