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For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8912182 B1

PDFFull Text
Date of Patent:
Dec. 16, 2014

Filed:

Aug. 15, 2013

Viral polymerase inhibitors

Applicants:

Pierre L. Beaulieu, Rosemere, CA;

Pasquale Forgione, Montreal, CA;

Alexandre Gagnon, Cambridge, MA (US);

Cedrickx Godbout, Laval, CA;

Marc-andre Joly, Terrebonne, CA;

Montse Llinas-brunet, Dollard-des-Ormeaux, CA;

Julie Naud, Blainville, CA;

Martin Poirier, Blainville, CA;

Jean Rancourt, Laval, CA;

Inventors:

Pierre L. Beaulieu, Rosemere, CA;

Pasquale Forgione, Montreal, CA;

Alexandre Gagnon, Cambridge, MA (US);

Cedrickx Godbout, Laval, CA;

Marc-Andre Joly, Terrebonne, CA;

Montse Llinas-Brunet, Dollard-des-Ormeaux, CA;

Julie Naud, Blainville, CA;

Martin Poirier, Blainville, CA;

Jean Rancourt, Laval, CA;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:

Michael P. Morris

David A. Dow

Primary Examiner:

Sun Jae Yoo

Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 213/81 (2006.01); C07D 213/643 (2006.01); C07D 239/34 (2006.01); A61K 31/444 (2006.01); C07D 215/227 (2006.01); C07D 217/24 (2006.01); C07D 239/38 (2006.01); C07D 401/06 (2006.01); C07D 417/14 (2006.01); C07D 307/20 (2006.01); C07D 471/04 (2006.01); C07D 239/47 (2006.01); C07D 239/52 (2006.01); C07D 413/06 (2006.01); C07D 249/04 (2006.01); C07D 213/69 (2006.01); A61K 31/5377 (2006.01); C07D 211/38 (2006.01); C07D 417/06 (2006.01); C07D 333/32 (2006.01);
U.S. Cl.
CPC ...
A61K 31/444 (2013.01); C07D 215/227 (2013.01); C07D 217/24 (2013.01); C07D 239/38 (2013.01); C07D 401/06 (2013.01); C07D 417/14 (2013.01); C07D 227/24 (2013.01); C07D 307/20 (2013.01); C07D 471/04 (2013.01); C07D 213/643 (2013.01); C07D 239/47 (2013.01); C07D 213/81 (2013.01); C07D 239/52 (2013.01); C07D 413/06 (2013.01); C07D 401/14 (2013.01); C07D 249/04 (2013.01); C07D 213/69 (2013.01); A61K 31/5377 (2013.01); C07D 211/38 (2013.01); C07D 239/34 (2013.01); C07D 417/06 (2013.01); C07D 333/32 (2013.01);
Abstract

Compounds of formula I: wherein X, R, R, R, R, Rand Rare defined herein, are useful as inhibitors of the hepatitis C virus NS5B polymerase.

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