The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2014
Filed:
Jan. 06, 2012
Makoto Kitade, Nagareyama, JP;
Satoshi Yamashita, Tsukuba, JP;
Shuichi Ohkubo, Hanno, JP;
Taiho Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
A novel bicyclic compound having an HSP90 inhibitory effect and a carcinostatic effect. A pharmaceutical agent based on the HSP90 inhibitory effect and useful in the prevention and/or treatment of a disease involving HSP90, particularly cancer. The compound has a general formula (I) or is a salt thereof wherein at least one of X, X, X, and Xrepresents N or N-oxide and the rest thereof are each independently C—R; any one or two of Y, Y, Y, and Yrepresent C—Rand the rest thereof are each independently CH or N; Rrepresents an optionally substituted monocyclic or bicyclic unsaturated heterocyclic group having 1 to 4 heteroatoms selected from N, S, and O; Rrepresents a hydrogen atom, an optionally substituted alkyl group having 1 to 6 carbon atoms etc.; Rrepresents a hydrogen atom, —CO—Retc.