The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2014

Filed:

Feb. 08, 2013
Applicant:

Astellas Pharma Inc., Chuo-ku, JP;

Inventors:

Fumie Takahashi, Tokyo, JP;

Sunao Imada, Tokyo, JP;

Toru Asano, Tokyo, JP;

Yoshihiro Kozuki, Tokyo, JP;

Junko Maeda, Tokyo, JP;

Koji Kato, Tokyo, JP;

Hidehiko Fukahori, Tokyo, JP;

Masahiko Shiwaku, Tokyo, JP;

Assignee:

Astellas Pharma Inc., Chuo-ku, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/497 (2006.01); C07D 413/14 (2006.01); C07D 403/14 (2006.01); C07D 403/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); A61K 31/5377 (2013.01); A61K 31/497 (2013.01);
Abstract

Provided is a novel compound which is an agent for treating rejection reactions in various organ transplantations, allergy diseases, autoimmune diseases, and hematologic tumor, and based on a PI3Kδ selective inhibitory action and/or an IL-2 production inhibitory action and/or a B cell proliferation inhibitory action (including an activation inhibitory action). The provided compound has a PI3Kδ selective inhibitory action, an IL-2 production inhibitory action, and/or a B cell proliferation inhibitory action, including an activation inhibitory action.


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