The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2014
Filed:
Sep. 21, 2012
Applicant:
Merz Pharma Gmbh & Co. Kgaa, Frankfurt am Main, DE;
Inventors:
Jürgen Frevert, Berlin, DE;
Volker Specht, Berlin, DE;
Assignee:
Merz Pharma GmbH & Co. KGaA, Frankfurt Au Main, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 39/00 (2006.01); C07K 1/00 (2006.01); C12N 9/96 (2006.01); C07K 14/33 (2006.01);
U.S. Cl.
CPC ...
C12N 9/96 (2013.01); C07K 14/33 (2013.01);
Abstract
The invention relates to a modified botulinum toxin comprising a natural heavy chain and a modified light chain, characterized in that the modification of the light chain resides in that it comprises (i) an extension of the chain on its N-terminus which has the structure —(C)-(tag)-(X)— in the direction from the N- to the C-terminal end, wherein