The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2014

Filed:

Feb. 08, 2012
Applicants:

Masayuki Fukumura, Mie, JP;

Mitsuo Kawano, Mie, JP;

Tetsuya Nosaka, Mie, JP;

Junpei Ohtsuka, Mie, JP;

Inventors:

Masayuki Fukumura, Mie, JP;

Mitsuo Kawano, Mie, JP;

Tetsuya Nosaka, Mie, JP;

Junpei Ohtsuka, Mie, JP;

Assignees:

Mie University, Mie, JP;

BioComo Inc., Mie, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/64 (2006.01); C12N 15/86 (2006.01); C12N 7/04 (2006.01); C12N 5/10 (2006.01); C12N 5/16 (2006.01);
U.S. Cl.
CPC ...
C12N 15/64 (2013.01);
Abstract

The present invention discloses a cell system, as a host cell to be infected with an F gene-deficient virus, which can constitutively and stably express the F protein, and a method for producing an F gene-deficient virus by utilizing the cell. A non-proliferative human parainfluenza type 2 virus vector is produced by co-culturing an F gene-deficient human parainfluenza type 2 virus with a Vero cell having the F gene of human parainfluenza type 2 virus in such a manner that the F gene is non-inducibly expressed, and isolating viral particles from a culture supernatant.


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