The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2014
Filed:
Mar. 15, 2007
Daniel Irimia, Charlestown, MA (US);
Xuanhong Cheng, Charlestown, MA (US);
Mehmet Toner, Wellesley, MA (US);
Utkan Demirci, Cambridge, MA (US);
William Rodriguez, Arlington, MA (US);
Daniel Irimia, Charlestown, MA (US);
Xuanhong Cheng, Charlestown, MA (US);
Mehmet Toner, Wellesley, MA (US);
Utkan Demirci, Cambridge, MA (US);
William Rodriguez, Arlington, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
The invention features methods, devices, and kits for the isolation of analytes (e.g., a cell). A sample containing a desired analyte is introduced into a microfluidic device containing moieties that bind the desired analyte. A shear stress is applied that is great enough to prevent binding of undesired analytes and low enough to allow binding of the analyte of interest. Once bound, the desired analytes can be analyzed (e.g., counted). The invention also features methods for determining a shear stress for isolating a desired analyte.