The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2014

Filed:

Sep. 19, 2013
Applicants:

Cedars-sinai Medical Center, Los Angeles, CA (US);

Arrogene Nanotechnology, Inc., Los Angeles, CA (US);

Inventors:

Julia Y. Ljubimova, Studio City, CA (US);

Keith L. Black, Los Angeles, CA (US);

Eggehard Holler, Los Angeles, CA (US);

Assignees:

Cedars-Sinai Medical Center, Los Angeles, CA (US);

Arrogene Nanotechnology, Inc., Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61P 35/00 (2006.01); C08F 8/30 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48692 (2013.01); A61K 47/482 (2013.01); A61K 47/48215 (2013.01);
Abstract

A drug delivery system for delivering a drug payload to a specific tissue or cell type is disclosed. The system includes a polymalic acid molecular scaffold which can be used for attaching a plurality of molecular modules. Molecular modules include targeting antibodies for promoting cellular uptake by a target cell, and pro-drugs for altering cellular metabolism, for example, a pro-drug that alters expression of protein kinase CK2.


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