The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2014

Filed:

Dec. 29, 2006
Applicants:

Iryna Ziabreva, Wardley Gateshead, GB;

Petra Henrich-noack, Beaumont, IE;

Juergen Goldschmidt, Magdeburg, DE;

Kathrin Baldauf, Magdeburg, DE;

Henning Scheich, Samswegen, DE;

Klaus G. Reymann, Niederndodeleben, DE;

Ulrich H. Schroeder, Eussenheim, DE;

Claudia Pforte, Schochwitz, DE;

Monika Riek-burchardt, Kloster Neuendorf, DE;

Inventors:

Iryna Ziabreva, Wardley Gateshead, GB;

Petra Henrich-Noack, Beaumont, IE;

Juergen Goldschmidt, Magdeburg, DE;

Kathrin Baldauf, Magdeburg, DE;

Henning Scheich, Samswegen, DE;

Klaus G. Reymann, Niederndodeleben, DE;

Ulrich H. Schroeder, Eussenheim, DE;

Claudia Pforte, Schochwitz, DE;

Monika Riek-Burchardt, Kloster Neuendorf, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 49/00 (2006.01); A61K 49/10 (2006.01); A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0002 (2013.01); A61K 49/103 (2013.01); A61K 51/0476 (2013.01); A61K 51/0478 (2013.01);
Abstract

The present invention relates to a diagnostic substance, containing at least one complex of lipophilic anions and metal ions, wherein the lipophilic anions are selected from the group comprising: triethylene tetramine dihydrochloride (TETA), ethyl cysteinate dimer (ECD), methoxyisobutylisonitrile (MIBI), HMPAO (d,l-hexamethylpropylene aminoxime), ethylenediamine N,N,N',N′-tetraacetanilide (EDTAN), dimethyldithiocarbamate (DMC) and diethyldithiocarbamate (DDC) and glycine N,N′-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis [N-(carboxymethyl)-1,1′-bis[2-(octadecyloxy)ethyl]ester (DP-109), and wherein the metal ions are selected from the group comprising thallium isotopes, lead isotopes, cobalt isotopes and manganese isotopes, together with solvents, adjuvants and/or vehicles. The diagnostic substance is used for investigating metabolic processes in the brain and/or central nervous system (CNS).


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