The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2014

Filed:

Jan. 27, 2012
Applicants:

Alessio Moriconi, L'Aquila, IT;

Gianluca Bianchini, L'Aquila, IT;

Andrea Aramini, L'Aquila, IT;

Laura Brandolini, L'Aquila, IT;

Chiara Liberati, Milan, IT;

Silvia Bovolenta, Milan, IT;

Andrea Beccari, L'Aquila, IT;

Simone Lorenzi, L'Aquila, IT;

Inventors:

Alessio Moriconi, L'Aquila, IT;

Gianluca Bianchini, L'Aquila, IT;

Andrea Aramini, L'Aquila, IT;

Laura Brandolini, L'Aquila, IT;

Chiara Liberati, Milan, IT;

Silvia Bovolenta, Milan, IT;

Andrea Beccari, L'Aquila, IT;

Simone Lorenzi, L'Aquila, IT;

Assignee:

Dompe' S.p.A., L'Aquila (AQ), IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/335 (2006.01); C07D 213/38 (2006.01); C07D 307/52 (2006.01); C07D 333/20 (2006.01); A61K 31/44 (2006.01); C07D 213/36 (2006.01); C07D 207/323 (2006.01); C07D 307/56 (2006.01); C07D 333/28 (2006.01);
U.S. Cl.
CPC ...
C07D 213/38 (2013.01); C07D 333/20 (2013.01); C07D 213/36 (2013.01); C07D 307/52 (2013.01); C07D 207/323 (2013.01); C07D 307/56 (2013.01); C07D 207/335 (2013.01); C07D 333/28 (2013.01);
Abstract

Compounds acting as selective antagonists of Transient Receptor Potential cation channel subfamily M member 8 (hereinafter referred to as TRPM8), having formula: Wherein Said compounds are useful in the prevention and treatment of pathologies depending on TRPM8 activity such as pain, inflammation, ischaemia, neurodegeneration, stroke, psychiatric disorders, inflammatory conditions and urological disorders.


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