The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2014
Filed:
Apr. 06, 2010
Applicants:
Donald T. Moir, Concord, MA (US);
Daniel Aiello, Worcester, MA (US);
Norton P. Peet, North Andover, MA (US);
John D. Williams, Worcester, MA (US);
Inventors:
Donald T. Moir, Concord, MA (US);
Daniel Aiello, Worcester, MA (US);
Norton P. Peet, North Andover, MA (US);
John D. Williams, Worcester, MA (US);
Assignee:
Microbiotix, Inc., Worcester, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/34 (2006.01); A61K 31/36 (2006.01); A61K 31/38 (2006.01); A61K 31/41 (2006.01); A61K 31/44 (2006.01); A61K 31/415 (2006.01); A61K 31/496 (2006.01); A61K 31/381 (2006.01); A61K 31/5375 (2006.01); A61K 31/4245 (2006.01); A61K 45/06 (2006.01); A61K 31/407 (2006.01); A61K 31/216 (2006.01); A61K 31/427 (2006.01); A61K 31/16 (2006.01); A61K 31/4184 (2006.01); A61K 31/429 (2006.01); A61K 31/167 (2006.01); A61K 31/4152 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4245 (2013.01); A61K 31/496 (2013.01); A61K 31/381 (2013.01); A61K 31/5375 (2013.01); A61K 45/06 (2013.01); A61K 31/407 (2013.01); A61K 31/216 (2013.01); A61K 31/427 (2013.01); A61K 31/16 (2013.01); A61K 31/34 (2013.01); A61K 31/4184 (2013.01); A61K 31/429 (2013.01); A61K 31/167 (2013.01); A61K 31/4152 (2013.01); A61K 31/36 (2013.01);
Abstract
Organic compounds showing the ability to inhibit effector toxin secretion or translocation mediated by bacterial type III secretion systems are disclosed. The disclosed type III secretion system inhibitor compounds are useful for combating infections by Gram-negative bacteria such asspp.,spp.,spp., enteropathogenic and enteroinvasive, andspp. having such type III secretion systems.