The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2014
Filed:
Jun. 03, 2011
Applicants:
Tadaaki Ohgiya, Saitama, JP;
Takeshi Murakami, Tokyo, JP;
Katsutoshi Miyosawa, Tokyo, JP;
Kimiyuki Shibuya, Saitama, JP;
Koichi Yamazaki, Tokyo, JP;
Taichi Kusakabe, Chiba, JP;
Inventors:
Tadaaki Ohgiya, Saitama, JP;
Takeshi Murakami, Tokyo, JP;
Katsutoshi Miyosawa, Tokyo, JP;
Kimiyuki Shibuya, Saitama, JP;
Koichi Yamazaki, Tokyo, JP;
Taichi Kusakabe, Chiba, JP;
Assignee:
Kowa Company, Ltd., Aichi, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); C07D 239/48 (2006.01); C07D 239/47 (2006.01);
U.S. Cl.
CPC ...
C07D 239/47 (2013.01);
Abstract
Substantially optically pure (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid, or a salt thereof, or a solvate thereof, which has actions of reducing amount of PCSK9 protein and increasing amount of LDL receptor.