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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8906887 B1

PDFFull Text
Date of Patent:
Dec. 09, 2014

Filed:

Aug. 07, 2009

C7-fluoro substituted tetracycline compounds

Applicants:

Jingye Zhou, Belmont, MA (US);

Xiao-yi Xiao, San Diego, CA (US);

Louis Plamondon, Belmont, MA (US);

Diana Katharine Hunt, Cambridge, MA (US);

Roger B. Clark, Lexington, MA (US);

Robert B. Zahler, Pennington, NJ (US);

Inventors:

Jingye Zhou, Belmont, MA (US);

Xiao-Yi Xiao, San Diego, CA (US);

Louis Plamondon, Belmont, MA (US);

Diana Katharine Hunt, Cambridge, MA (US);

Roger B. Clark, Lexington, MA (US);

Robert B. Zahler, Pennington, NJ (US);

Assignee:

Tetraphase Pharmaceuticals, Inc., Watertown, MA (US);

Attorney:

Hamilton, Brook, Smith & Reynolds, P.C.

Primary Examiner:

Barbara P Badio

Int. Cl.
CPC ...
A61K 31/65 (2006.01); C07C 237/26 (2006.01); C07D 233/61 (2006.01); C07D 207/34 (2006.01); C07D 295/088 (2006.01); C07D 211/60 (2006.01); C07D 257/04 (2006.01); C07D 295/15 (2006.01); C07D 209/94 (2006.01); C07D 231/14 (2006.01); A61K 45/06 (2006.01); C07D 207/14 (2006.01); C07D 333/34 (2006.01); C07C 311/08 (2006.01); C07D 231/56 (2006.01); C07C 311/21 (2006.01); C07D 207/10 (2006.01); C07D 413/12 (2006.01); C07D 213/81 (2006.01); C07D 249/04 (2006.01); C07D 261/20 (2006.01); C07D 207/09 (2006.01); C07D 239/42 (2006.01); C07D 333/38 (2006.01); C07D 277/56 (2006.01); C07D 207/08 (2006.01); C07D 231/12 (2006.01); C07D 207/12 (2006.01); C07D 213/82 (2006.01); C07D 205/04 (2006.01); C07D 295/26 (2006.01); C07D 207/16 (2006.01); C07D 261/18 (2006.01); C07D 211/76 (2006.01); C07D 213/74 (2006.01);
U.S. Cl.
CPC ...
A61K 31/65 (2013.01); C07D 233/61 (2013.01); C07D 207/34 (2013.01); C07D 295/088 (2013.01); C07D 211/60 (2013.01); C07D 257/04 (2013.01); C07D 295/15 (2013.01); C07D 209/94 (2013.01); C07D 231/14 (2013.01); A61K 45/06 (2013.01); C07D 207/14 (2013.01); C07D 333/34 (2013.01); C07C 311/08 (2013.01); C07D 231/56 (2013.01); C07C 311/21 (2013.01); C07D 207/10 (2013.01); C07D 413/12 (2013.01); C07D 213/81 (2013.01); C07D 249/04 (2013.01); C07D 261/20 (2013.01); C07D 207/09 (2013.01); C07D 239/42 (2013.01); C07D 333/38 (2013.01); C07D 277/56 (2013.01); C07D 207/08 (2013.01); C07D 231/12 (2013.01); C07D 207/12 (2013.01); C07D 213/82 (2013.01); C07D 205/04 (2013.01); C07D 295/26 (2013.01); C07D 207/16 (2013.01); C07D 261/18 (2013.01); C07D 211/76 (2013.01); C07D 213/74 (2013.01);
Abstract

The present invention is directed to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (A) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (A) and its therapeutic use.

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