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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8906857 B1

PDFFull Text
Date of Patent:
Dec. 09, 2014

Filed:

Feb. 03, 2009

Methods for the diagnosis and treatment of critically ill patients with endothelin, endothelin agonists and adrenomedullin antagonists

Applicants:

Andreas Bergmann, Berlin, DE;

Joachim Struck, Berlin, DE;

Nils G. Morgenthaler, Berlin, DE;

Inventors:

Andreas Bergmann, Berlin, DE;

Joachim Struck, Berlin, DE;

Nils G. Morgenthaler, Berlin, DE;

Assignee:

B.R.A.H.M.S. GmbH, Hennigsdorf, DE;

Attorney:

Millen, White, Zelano, Branigan, P.C.

Primary Examiner:

Marianne P Allen

Int. Cl.
CPC ...
A61K 39/395 (2006.01); G01N 33/53 (2006.01); A61K 38/17 (2006.01); G01N 33/74 (2006.01); C07K 16/22 (2006.01); C07K 16/26 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); G01N 2800/60 (2013.01); G01N 33/74 (2013.01); G01N 2333/575 (2013.01); G01N 2333/5754 (2013.01); C07K 16/26 (2013.01);
Abstract

The ratio of concentrations of pro-adrenomedullin (pro-ADM)/pro-endothelin (pro-END) immunoreactivity in body fluids of critically ill patients is used as for the diagnosis, course control and prognosis, including an assessment of the mortality risk, of severe life threatening diseases. Further, a treatment of critically ill patients having high levels of pro-ADM but insufficient levels of pro-END immunoreactivities with a medicament comprising vasoconstrictive endothelin or its precursors, and/or endothelin agonists or adrenomedullin antagonists is provided.

Find Patent Forward Citations

Bergmann, Andreas. (2014). Methods for the diagnosis and treatment of critically ill patients with endothelin, endothelin agonists and adrenomedullin antagonists (U.S. Patent No. 8906857). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8906857

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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